3-氨基-4-羟基-苯甲酰胺合成路线 （共 4 条）
反应条件
hydrogen; palladium on activated charcoal in methanol 1 h;
参考文献
Cone, Martha C.; Melville, Chris R.; Carney, John R.; Gore, Makarand P.; Gould, Steven J.
Tetrahedron, 1995 , vol. 51, # 11 p. 3095 - 3102
反应条件
1: 31 percent / aq. NH3 / 48 h / 50 - 60 °C 2: 89 percent / H2 / Pd/C / methanol / 3 h / 2327.17 Torr View Scheme
参考文献
Sun, Aiming; Prussia, Andrew; Zhan, Weiqiang; Murray, Ernest E.; Doyle, Joshua; Cheng, Li-Ting; Yoon, Jeong-Joong; Radchenko, Eugene V.; Palyulin, Vladimir A.; Compans, Richard W.; Liotta, Dennis C.; Plemper, Richard K.; Snyder, James P.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 17 p. 5080 - 5092
反应条件
1: 82 percent / diisopropylamine / CH2Cl2 2: 31 percent / aq. NH3 / 48 h / 50 - 60 °C 3: 89 percent / H2 / Pd/C / methanol / 3 h / 2327.17 Torr View Scheme
参考文献
Sun, Aiming; Prussia, Andrew; Zhan, Weiqiang; Murray, Ernest E.; Doyle, Joshua; Cheng, Li-Ting; Yoon, Jeong-Joong; Radchenko, Eugene V.; Palyulin, Vladimir A.; Compans, Richard W.; Liotta, Dennis C.; Plemper, Richard K.; Snyder, James P.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 17 p. 5080 - 5092
反应条件
in thionyl chloride; toluene
参考文献
ICI Americas Inc.
Patent: US5164371 A1, 1992 ;
