1.1: Pearlman's catalyst; hydrogen / ethyl acetate / 18 h / 2327.23 Torr / Large scale reaction 2.1: 1,1'-carbonyldiimidazole / ethyl acetate / 2 h / 10 - 20 °C / Inert atmosphere; Large scale reaction 2.2: 30 °C / Inert atmosphere; Large scale reaction 3.1: sodium tetrahydroborate; BF3*THF / tetrahydrofuran / 20 - 37 °C / Inert atmosphere; Large scale reaction View Scheme

With  hydrogen; Pearlman's catalist in  ethyl acetate T=15 - 32°C; P=3087.28 Torr; 18 h;  Inert atmosphere;  Show Experimental Procedure  

Multi-step reaction with 2 steps 1.1: Pearlman's catalyst; hydrogen / ethyl acetate / 18 h / 2327.23 Torr / Large scale reaction2.1: 1,1'-carbonyldiimidazole / ethyl acetate / 2 h / 10 - 20 °C / Inert atmosphere; Large scale reaction2.2: 30 °C / Inert atmosphere; Large scale reaction