5-溴-3-氟-2-(羟基甲基)吡啶合成路线 （共 2 条）
反应条件
sodium tetrahydroborate in ethanol
4 h; Reflux;
参考文献
GLAXOSMITHKLINE LLC; ADAMS, Nicholas, David; CHAUDHARI, Amita, M.; KIESOW, Terence, John; McSHERRY, Allison, K.; MOORE, Michael, Lee; PARRISH, Cynthia, Ann; REIF, Alexander, Joseph; RIDGERS, Lance, Howard
Patent: WO2014/8223 A2, 2014 ;
Location in patent: Page/Page column 133-134 ;
反应条件
1: sulfuric acid / 4 h / 80 °C
2: sodium tetrahydroborate / ethanol / 4 h / |Reflux
View Scheme
参考文献
GLAXOSMITHKLINE LLC; ADAMS, Nicholas, David; CHAUDHARI, Amita, M.; KIESOW, Terence, John; McSHERRY, Allison, K.; MOORE, Michael, Lee; PARRISH, Cynthia, Ann; REIF, Alexander, Joseph; RIDGERS, Lance, Howard
Patent: WO2014/8223 A2, 2014 ;
