N-Boc-1-氨基环丁烷羧酸合成路线 （共 13 条）
反应条件
sulfuric acid T=0°C; Reflux;
参考文献
GRUENENTHAL GmbH
Patent: US2010/173889 A1, 2010 ;
Location in patent: Page/Page column 34 ;
反应条件
1: With borane-THF in tetrahydrofuran T=-10°C; 2: With water; acetic acid in tetrahydrofuran
参考文献
ACHAOGEN, INC.; BRUSS, Jon, B.; MILLER, George, H.; AGGEN, James, Bradley; ARMSTRONG, Eliana, Saxon
Patent: WO2010/132777 A2, 2010 ;
Location in patent: Page/Page column 195; 48-49 ;
反应条件
1: potassium carbonate / acetone 2: trifluoroacetic acid / dichloromethane / 1 h / 20 °C View Scheme
参考文献
Bremner, John B.; Keller, Paul A.; Pyne, Stephen G.; Robertson, Mark J.; Sakthivel; Somphol, Kittiya; Baylis, Dean; Coates, Jonathan A.; Deadman, John; Jeevarajah, Dharshini; Rhodes, David I.
Beilstein Journal of Organic Chemistry, 2012 , vol. 8, p. 1265 - 1270
