1-苄基-4-boc-哌嗪合成路线 (共 4 条)
反应条件
1: in dichloromethane T=20°C; 2: With sodium hydrogencarbonate in dichloromethane; water
参考文献
ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2007/135427 A1, 2007 ;
Location in patent: Page/Page column 31 ;
WO 2007/135427 A1
反应条件
[Cp*IrCl2]2; sodium hydrogencarbonate in toluene T=110°C; 17 h; Inert atmosphere;
参考文献
Fujita, Ken-Ichi; Kida, Yasushi; Yamaguchi, Ryohei
Heterocycles, 2009 , vol. 77, # 2 p. 1371 - 1377
参考文献
Janssen Pharmaceutica N.V.
Patent: US4880808 A1, 1989 ;
反应条件
hydrogen; Pearlman's catalyst in ethanol T=20°C; P=1861.78 Torr;
参考文献
WO2007/135427 A1, ;
Page/Page column 31 ;
WO 2007/135427 A1