4-氯甲基-2,6-二甲基吡啶合成路线 （共 3 条）
反应条件
1: With thionyl chloride in dichloromethane T=20°C; 21 h; 2: With water; sodium hydrogencarbonate
参考文献
ASKA Pharmaceutical Co., Ltd.
Patent: EP2036905 A1, 2009 ;
Location in patent: Page/Page column 50 ;
反应条件
triethylamine in dichloromethane T=20°C; 1 h;
参考文献
BIOVITRUM AB (publ)
Patent: WO2009/147211 A1, 2009 ;
Location in patent: Page/Page column 27 ;
WO 2009/147211 A1
反应条件
bis(trichloromethyl) carbonate; diisopropylamine in dichloromethane T=-20 - 20°C;
参考文献
Narendar; Gangadasu; Ramesh, Ch.; Raju, B. China; Rao, V. Jayathirtha
Synthetic Communications, 2004 , vol. 34, # 6 p. 1097 - 1103
