1.1: isopropylmagnesium chloride / tetrahydrofuran / 3 h / -78 °C / Inert atmosphere 1.2: -78 - 25 °C / Inert atmosphere 2.1: dihydrogen peroxide; sodium hydroxide / tetrahydrofuran; water / 0 - 25 °C / Inert atmosphere 3.1: potassium carbonate / acetone / 18 h / Reflux 4.1: isopropylmagnesium chloride / tetrahydrofuran / 3 h / -78 °C / Inert atmosphere 4.2: -78 - 25 °C / Inert atmosphere 5.1: dihydrogen peroxide; sodium hydroxide / tetrahydrofuran; water / 0 - 25 °C / Inert atmosphere 6.1: potassium carbonate / acetone / 18 h / Reflux View Scheme

Multi-step reaction with 3 steps 1.1: isopropylmagnesium chloride / tetrahydrofuran / 3 h / -78 °C / Inert atmosphere1.2: -78 - 25 °C / Inert atmosphere2.1: dihydrogen peroxide; sodium hydroxide / tetrahydrofuran; water / 0 - 25 °C / Inert atmosphere3.1: potassium carbonate / acetone / 18 h / Reflux  

Multi-step reaction with 4 steps 1.1: isopropylmagnesium chloride / tetrahydrofuran / 3 h / -78 °C / Inert atmosphere1.2: -78 - 25 °C / Inert atmosphere2.1: dihydrogen peroxide; sodium hydroxide / tetrahydrofuran; water / 0 - 25 °C / Inert atmosphere3.1: potassium carbonate / acetone / 18 h / Reflux4.1: isopropylmagnesium chloride / tetrahydrofuran / 3 h / -78 °C / Inert atmosphere4.2: -78 - 25 °C / Inert atmosphere  

Multi-step reaction with 5 steps 1.1: isopropylmagnesium chloride / tetrahydrofuran / 3 h / -78 °C / Inert atmosphere1.2: -78 - 25 °C / Inert atmosphere2.1: dihydrogen peroxide; sodium hydroxide / tetrahydrofuran; water / 0 - 25 °C / Inert atmosphere3.1: potassium carbonate / acetone / 18 h / Reflux4.1: isopropylmagnesium chloride / tetrahydrofuran / 3 h / -78 °C / Inert atmosphere4.2: -78 - 25 °C / Inert atmosphere5.1: dihydrogen peroxide; sodium hydroxide / tetrahydrofuran; water / 0 - 25 °C / Inert atmosphere