4-氯-7h-吡咯并[2,3-d]嘧啶-5-羧酸甲酯合成路线 （共 1 条）
反应条件
1: 5-bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine With n-butyllithium in tetrahydrofuran; hexanes T=-78°C; 2: methyl chloroformate in tetrahydrofuran; hexanes T=-78 - 20°C;
参考文献
NOVARTIS AG; CHEN, Yen-Liang; DURAISWAMY, Jeyaraj; KONDREDDI, Ravinder Reddy; YIN, Zheng
Patent: WO2010/15637 A1, 2010 ;
Location in patent: Page/Page column 94-95 ;
