1: 50 percent / Et3N / CH2Cl2 / 24 h / Ambient temperature 2: 1.) O3, 2.) Me2S / 1) CH2Cl2, MeOH, -78 deg C; 2) CH2Cl2, MeOH, 4 h 3: 80 percent / immobilized penicillin acylase / ethanol / 0.5 h / 23 °C / pH 7.5 View Scheme

(η5-Me5C5)2SmCH(Me3Si)2 in benzene 96 h; Ambient temperature;