2-溴-1,4-二氟-3-甲氧基苯合成路线 （共 2 条）
反应条件
potassium carbonate in acetonitrile T=150°C; 0.166667 h; Microwave irradiation;
参考文献
Janssen Pharmaceuticals, Inc.; Andrés-Gil, José Ignacio; Alcázar-Vaca, Manuel Jesús; Cid-Núñez, José Maria; Trabanco-Suárez, Andrés Avelino; Bormans, Guy Maurits R.; Celen, Sofie Jeanne Leopoldine; Koole, Michel
Patent: US2013/230459 A1, 2013 ;
Location in patent: Paragraph 0176 ;
反应条件
1: N-bromosuccinmide; isopropylamine / tetrahydrofuran / -40 - 20 °C 2: potassium carbonate / acetonitrile / 0.17 h / 150 °C / Microwave irradiation View Scheme
参考文献
Janssen Pharmaceuticals, Inc.; Andrés-Gil, José Ignacio; Alcázar-Vaca, Manuel Jesús; Cid-Núñez, José Maria; Trabanco-Suárez, Andrés Avelino; Bormans, Guy Maurits R.; Celen, Sofie Jeanne Leopoldine; Koole, Michel
Patent: US2013/230459 A1, 2013 ;
