反应条件
t-butyl lithium; hydrochloric acid; SnCl2 in diethyl ether; water; pentane Schlenk techniques used under Ar, Fc(C4H6O2)CH2OMe (20 mmol) in Et2O treated with 1.7M pentane soln. of tBuLi (22 mmol) at -78°C for 10 min, stirred for 1 h at room temp., cooled to -20°C, CO2 gas introduced for 20 min, aq. HCl/SnCl2 added; stirred overnight at room temp., organic phase sepd., aq. phase extd. with EtOAc, combined organic phase washed with H2O, dried over Na2SO4, evapd., chromd. (SiO2, CH2Cl2/MeOH (80:1, 30:1)), evapd., petroleum ether added, filtered, dried; elem. anal.;
参考文献
Journal of Organometallic Chemistry, , vol. 696, # 8 p. 1626 - 1631
