1.1: dichloromethane / -15 - 15 °C / Large scale reaction 1.2: Large scale reaction 2.1: sodium hydrogencarbonate; sodium carbonate; sodium sulfite / dichloromethane; water / 1.25 h / 5 - 20 °C / pH 7 - 10 / Large scale reaction View Scheme
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Allwein, Shawn P.; Roemmele, Renee C.; Haley, James J.; Mowrey, Dale R.; Petrillo, Daniel E.; Reif, James J.; Gingrich, Diane E.; Bakale, Roger P.
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15 h; Irradiation; Further byproducts given. Title compound not separated from byproducts;
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Khimiya Geterotsiklicheskikh Soedinenii, , # 8 p. 1033 - 1041
oxidation with Pseudomonas BM2 and other mutant; Product distribution;
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