2-氨基-5-硝基苯酚合成路线 （共 116 条）
反应条件
sodium hydroxide in dimethyl sulfoxide
参考文献
Clairol Incorporated
Patent: US5055110 A1, 1991 ;
反应条件
sodium acetate in ethanol
24 h;
参考文献
Bedernjak, Alexandre F.; Groundwater, Paul W.; Gray, Mark; James, Arthur L.; Orenga, Sylvain; Perry, John D.; Anderson, Rosaleen J.
Tetrahedron, 2013 , vol. 69, # 39 p. 8456 - 8462
反应条件
1: aq. ethanol / 0.5 h / Ambient temperature
2: Pb(OAc)4 / acetonitrile / 0.08 h / Heating
View Scheme
参考文献
Haugwitz; Angel; Jacobs; Maurer; Narayanan; Cruthers; Szanto
Journal of Medicinal Chemistry, 1982 , vol. 25, # 8 p. 969 - 974
反应条件
1: aq. ethanol / 0.5 h / Ambient temperature
2: Pb(OAc)4 / acetonitrile / 0.08 h / Heating
3: H2 / PtO2 / ethanol / 2585.7 Torr
4: triethylamine / tetrahydrofuran / 3 h / Ambient temperature
View Scheme
参考文献
Haugwitz; Angel; Jacobs; Maurer; Narayanan; Cruthers; Szanto
Journal of Medicinal Chemistry, 1982 , vol. 25, # 8 p. 969 - 974
反应条件
hydrogenchloride; tin(ll) chloride
参考文献
Tsao, Yu-Chi; Rej, Sourav; Chiu, Chun-Ya; Huang, Michael H.
Journal of the American Chemical Society, 2014 , vol. 136, # 1 p. 396 - 404
反应条件
1: glacial acetic acid
2: alkali
View Scheme
参考文献
Morgan; Porter
Journal of the Chemical Society, 1915 , vol. 107, p. 652
反应条件
in tetrahydrofuran
T=20°C; 24 h;
参考文献
4SC AG
Patent: EP1674466 A1, 2006 ;
Location in patent: Page/Page column 23 ;
EP 1674466 A1
反应条件
sodium hydrogencarbonate in acetone
参考文献
Agfa Gevaert AG
Patent: DE2156480 , 1972 ;
Chem.Abstr., 1972 , vol. 77, # 141498
反应条件
potassium carbonate; 4-(N,N-dimethlyamino)pyridine in tetrahydrofuran
T=23°C; 4 h;
参考文献
Boger,D.L.; Coleman,R.S.
Journal of the American Chemical Society, 1988 , vol. 110, p. 4796
反应条件
sodium hydrogencarbonate in acetone
参考文献
Agfa Gevaert AG
Patent: DE2156480 , 1972 ;
Chem.Abstr., 1972 , vol. 77, # 141498
