甲基4-甲氧基苯甲酸酯合成路线 (共 354 条)
参考文献
Chemische Berichte, , vol. 35, p. 3030
Chemische Berichte, , vol. 37, p. 2870
反应条件
1: 1-bromo-4-methoxy-benzene With magnesium in tetrahydrofuran Reflux; 2: methyl 4-(N-tert-butoxycarbonyl-(5S)-methyl-(2S)-pyrrolidinylmethoxy)benzoate in tetrahydrofuran T=20°C; Reflux;
参考文献
Horn, Markus; Mayr, Herbert
Chemistry - A European Journal, 2010 , vol. 16, # 25 p. 7469 - 7477
反应条件
in tetrahydrofuran Heating;
参考文献
Lucas, C. Robert
Canadian Journal of Chemistry, 1986 , vol. 64, p. 1758 - 1763
反应条件
1: 47.2 percent / H2 / 5percent Rh/Alumina / acetic acid / 2585.7 Torr 2: 63.3 percent / KOH / ethanol / 24 h / Heating View Scheme
参考文献
Krapcho, A.Paul; Dundulis, Edward A.
Journal of Organic Chemistry, 1980 , vol. 45, # 16 p. 3236 - 3245
反应条件
boron trifluoride diethyl etherate in toluene 2 h; Heating;
参考文献
Bello, Angelica M.; Kotra, Lakshmi P.
Tetrahedron Letters, 2003 , vol. 44, # 52 p. 9271 - 9274
反应条件
Triethylgermyl-natrium in tetrahydrofuran; N,N,N',N',N'',N''-hexamethylphosphoric triamide T=-60°C; 1.5 h;
参考文献
Yokoyama, Yasuo; Mochida, Kunio
Synlett, 1997 , vol. 1997, # 8 p. 907 - 908
反应条件
1: With tetra-n-butylammonium acetate in toluene T=0 - 20°C; 1 h; 2: With hydrogenchloride in tetrahydrofuran; toluene
参考文献
Kawano, Yoshikazu; Kaneko, Nobuya; Mukaiyama, Teruaki
Bulletin of the Chemical Society of Japan, 2006 , vol. 79, # 7 p. 1133 - 1145
反应条件
1: 1) lithium 2,2,6,6-tetramethylpiperidide / 1) -10 degC, THF, 2) 0 degC, 20 min 2: 1) lithium 2,2,6,6-tetramethylpiperidide / 1) -10 degC, THF, 2) 0 degC, 20 min View Scheme
参考文献
Bartoli, Giuseppe; Palmieri, Gianni; Petrini, Marino
Tetrahedron, 1990 , vol. 46, # 4 p. 1379 - 1384
反应条件
strontium in tetrahydrofuran T=20°C; Barbier reaction; 0.5 h;
参考文献
European Journal of Organic Chemistry, , # 20 p. 4253 - 4255
反应条件
magnesium 1.) ether, reflux, 0.5 h, 2.) ether, reflux, 2 h; Yield given. Multistep reaction;
参考文献
Hartmann, Rolf W.; Kranzfelder, Gerhard; Angerer, Erwin, v.; Schoenenberger, Helmut
Journal of Medicinal Chemistry, 1980 , vol. 23, # 8 p. 841 - 848