甲基4-甲氧基苯甲酸酯合成路线 （共 354 条）
反应条件
titanium(IV) isopropylate in tetrahydrofuran T=20°C; Kulinkovich reaction;
参考文献
Jingliang, Jiao; Nguyen, Larry X.; Patterson, Dennis R.; Flowers II, Robert A.
Organic Letters, 2007 , vol. 9, # 7 p. 1323 - 1326
参考文献
The Upjohn Company
Patent: US5412141 A1, 1995 ;
反应条件
n-butyllithium 1.) ether, hexane, reflux, 30 min, 2.) ether, hexane, reflux, 30 min; Yield given. Multistep reaction;
参考文献
Nugent; Schlachter; Murphy; Dunn; Staite; Galinet; Shields; Wu; Aspar; Richard
Journal of Medicinal Chemistry, 1994 , vol. 37, # 26 p. 4449 - 4454
反应条件
1.1: hydrazine hydrate / Reflux 2.1: potassium hydroxide / methanol / 0.25 h 2.2: 3 h / 20 - 25 °C 3.1: hydrazine hydrate / water / 1 h / Reflux View Scheme
参考文献
Kotaiah; Nagaraju; Harikrishna; Venkata Rao; Yamini; Vijjulatha
European Journal of Medicinal Chemistry, 2014 , vol. 75, p. 195 - 202
反应条件
1: 94.4 percent / LiAlH4 / diethyl ether / 4 h / Heating 2: 93.8 percent / SOCl2 / diethyl ether / 3 h / 20 °C 3: 4 h / Heating View Scheme
参考文献
Chen, Guoliang; Shan, Wei; Wu, Yingliang; Ren, Lixiang; Dong, Jinhua; Ji, Zhizhong
Chemical and Pharmaceutical Bulletin, 2005 , vol. 53, # 12 p. 1587 - 1590
反应条件
1: 81 percent / KOH / methanol; H2O / 4 h / Heating 2: thionyl chloride / 1 h / Heating View Scheme
参考文献
Bourne, David J.; Barrow, Kevin D.; Milborrow, B. V.
Phytochemistry (Elsevier), 1991 , vol. 30, # 12 p. 4041 - 4044
反应条件
tetra-n-butylammonium tetrafluoroborate in N,N-dimethyl-formamide Ambient temperatureconstant current electrolysis (0.2 A, cadmium coated cathode, magnesium anode);
参考文献
Heintz, Monique; Devaud, Marguerite; Hebri, Hassan; Dunach, Elisabet; Troupel, Michel
Tetrahedron, 1993 , vol. 49, # 11 p. 2249 - 2252
反应条件
1: ethanol / Heating 2: HCl(conc) / methanol / 4 h / Heating 3: aq. NaOH / 4 h / Heating View Scheme
参考文献
Balse, Mukta N.; Mahajanshetti, C. S.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1980 , vol. 19, # 4 p. 260 - 262
反应条件
1: 75 percent / titanium tetraisopropoxide / tetrahydrofuran / 20 °C 2: 75 percent / KBr; cerium(IV) ammonium nitrate / CH2Cl2; H2O / 0.5 h / 20 °C View Scheme
参考文献
Jingliang, Jiao; Nguyen, Larry X.; Patterson, Dennis R.; Flowers II, Robert A.
Organic Letters, 2007 , vol. 9, # 7 p. 1323 - 1326
反应条件
1: With [CpFe(CO)2(PCy3)][BF4]; phenyl silane T=100°C; 24 h; IrradiationNeat (no solvent)Inert atmosphere; 2: With hydrogenchloride; water in tetrahydrofuran T=20°C; 1 h;
参考文献
Bezier, David; Venkanna, Gopaladasu T.; Castro, Luis C. Misal; Zheng, Jianxia; Roisnel, Thierry; Sortais, Jean-Baptiste; Darcel, Christophe
Advanced Synthesis and Catalysis, 2012 , vol. 354, # 10 p. 1879 - 1884
