甲基4-甲氧基苯甲酸酯合成路线 （共 354 条）
反应条件
1: 1.) LDA / 1.) THF, 2.) THF, -78 deg C View Scheme
参考文献
Satoh; Mizu; Hayashi; Yamakawa
Tetrahedron Letters, 1994 , vol. 35, # 1 p. 133 - 134
反应条件
hydrogen; Rh/Al2O3 in acetic acid P=2585.7 Torr;
参考文献
Krapcho, A.Paul; Dundulis, Edward A.
Journal of Organic Chemistry, 1980 , vol. 45, # 16 p. 3236 - 3245
参考文献
Wahl; Silberzweig
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1910 , vol. 150, p. 540
Bulletin de la Societe Chimique de France, 1912 , vol. <4> 11, p. 64
反应条件
1: 95 percent / hydrazine hydrate / ethanol 2: 81 percent / dimethylformamide View Scheme
参考文献
Murty; Ramalingeswara Rao; Katiki, Mohana Rao; Nath, Lekshmi R.; Anto, Ruby John
Medicinal Chemistry Research, 2013 , vol. 22, # 10 p. 4980 - 4991
反应条件
sodium hydride in ethylene glycol dimethyl ether; paraffin 4 h; Heating;
参考文献
Specht, Donald P.; Martic, Peter A.; Farid, Samir; ++
Tetrahedron, 1982 , vol. 38, # 9 p. 1203 - 1211
反应条件
1: 87 percent / LDA / tetrahydrofuran / 0.5 h / -65 °C 2: 60 percent / EtMgBr / tetrahydrofuran / 2 h / -70 - -40 °C View Scheme
参考文献
Satoh Tsuyoshi; Mizu, Yasuhiro; Kawashima, Taku; Yamakawa, Koji
Tetrahedron, 1995 , vol. 51, # 3 p. 703 - 710
反应条件
chlorosulfonic acid T=0 - 20°C;
参考文献
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE; PINKERTON, Anthony, B.; DAHL, Russell; COSFORD, Nicholas, D.P.; MILLAN, Jose, Luis
Patent: WO2013/126608 A1, 2013 ;
Location in patent: Paragraph 00214 ;
反应条件
tetraethylammonium p-toluenesulfonate Electrochemical reactionSn cathode; Pt anode; constant current 0.2 A; divided cell;
参考文献
Kise; Hirata; Ueda
Journal of Organic Chemistry, 2001 , vol. 66, # 3 p. 862 - 867
反应条件
1: 1-(4-methoxyphenyl)ethanone With lithium hexamethyldisilazane in toluene T=0°C; 2: methyl 4-(N-tert-butoxycarbonyl-(5S)-methyl-(2S)-pyrrolidinylmethoxy)benzoate in toluene Further stages.;
参考文献
Dhondi, Pawan K.; Carberry, Patrick; Chisholm, John D.
Tetrahedron Letters, 2007 , vol. 48, # 49 p. 8743 - 8746
反应条件
1: potassium hydroxide / 4 h / pH 1-2 / |Reflux 2: thionyl chloride / 6 h / |Reflux 3: acetonitrile / 1.5 h / |Reflux View Scheme
参考文献
Huang, Yao-Dong; Dong, Xue-Lin; Zhang, Li-Li; Chai, Wei; Chang, Ji-Young
Journal of Molecular Structure, 2013 , vol. 1031, p. 43 - 48
