反应条件
1: 1.) benzenesulfonic acid, 2.) hydroxylamine hydrochloride, sodium acetate, sodium hydroxide / 1.) benzene, reflux, 1 h, 2.) ethanol, reflux, 15 min
2: LiAlH4 / diethyl ether / 24 h / 25 °C
3: concd. aq. HCl / 20 h
4: 17 percent / lithium diisopropylamide (LDA) / hexane; tetrahydrofuran / 1.) -78 deg C, 3 h, 2.) 50 deg C, 48 h
View Scheme
参考文献
Weitzberg, Moshe; Abu-Shakra, Elias; Azeb, Abdullatif; Aizenshtat, Zeev; Blum, Jochanan
Journal of Organic Chemistry, 1987 , vol. 52, # 4 p. 529 - 536
