10,11-二氢二苯并[a,b]环庚烯-5-酮合成路线 （共 77 条）
反应条件
1: 2: With hydrogenchloride in ethanol; water Heating / reflux;
参考文献
UNIVERSITY OF VIRGINIA PATENT FOUNDATION
Patent: WO2006/23757 A2, 2006 ;
Location in patent: Page/Page column 37 ;
WO 2006/023757 A2
反应条件
(i) Mg, (ii) /BRN= 1454355/, (iii) TsOH; Multistep reaction;
参考文献
Hoffsommer,R.D. et al.
Journal of Organic Chemistry, 1963 , vol. 28, p. 1751 - 1753
反应条件
1: (i) Mg, (ii) /BRN= 1454355/, THF 2: aq. HI, phosphorus View Scheme
参考文献
Winthrop,S.O. et al.
Journal of Organic Chemistry, 1962 , vol. 27, p. 230 - 240
反应条件
tetrachloromethane; N-bromosuccinmide
参考文献
Cope; Fenton
Journal of the American Chemical Society, 1951 , vol. 73, p. 1668,1672
Full Text Show Details
Bergmann et al.
Bulletin de la Societe Chimique de France, 1951 , p. 669,680
反应条件
1: 100 percent / sodium bis(trimethylsilyl)amide / dioxane; tetrahydrofuran / 2 h / Heating 2: 81 percent / aq. HClO4 / diethyl ether / 20 °C 3: 81 percent / NaBH4 / ethanol / 4 h / 20 °C View Scheme
参考文献
Wright; Platz
Journal of the American Chemical Society, 1984 , vol. 106, # 15 p. 4175 - 4180
反应条件
(i) Mg, (ii) /BRN= 1454355/, THF; Multistep reaction;
参考文献
Winthrop,S.O. et al.
Journal of Organic Chemistry, 1962 , vol. 27, p. 230 - 240
反应条件
iodine; hypophosphorous ether in acetic acid Reduction; 24 h; Heating;
参考文献
Hicks; Han; Fry
Tetrahedron Letters, 2000 , vol. 41, # 41 p. 7817 - 7820
反应条件
1: sodium tetrahydroborate; sodium hydroxide / methanol 2: quartz / 350 - 650 °C / Inert atmosphere; Pyrolysis 3: sodium tetrahydroborate; sodium hydroxide / methanol 4: H-ZSM-5 β mesoporous zeolite / 300 °C / Inert atmosphere; Pyrolysis View Scheme
参考文献
Istrati, Daniela; Parvulescu, Luminitza; Popescu, Angela; Mihaiescu, Dan; Badea, Florin
Revue Roumaine de Chimie, 2010 , vol. 55, # 10 p. 711 - 714
反应条件
1: pyridine; hydroxylamine hydrochloride / ethanol / 15 h / |Reflux 2: Eaton’s reagent / 0.5 h / 100 °C / |Inert atmosphere View Scheme
参考文献
Chadwick, Ryan C.; Van Gyzen, Sabrina; Liogier, Sophie; Adronov, Alex
Synthesis (Germany), 2014 , vol. 46, # 5 p. 669 - 677
反应条件
1.1: magnesium; I2 / tetrahydrofuran / Heating 1.2: 68 percent / tetrahydrofuran / 0 - 20 °C 2.1: 63 percent / aq. HCl / ethanol / Heating View Scheme
参考文献
Kupracz, Lukas; Kirschning, Andreas
Advanced Synthesis and Catalysis, 2013 , vol. 355, # 17 p. 3375 - 3380
