1: anhydrous 1-octyne With n-butyllithium in diethyl ether; hexane T=-78°C; 3 h; 2: tri-isopropoxy-borane in diethyl ether; hexane T=-78 - 20°C; 3 h;

cesium fluoride; tetrakis(triphenylphosphine) palladium(0) in ethylene glycol dimethyl ether Arylation; Suzuki-Miyaura cross-coupling reaction; 4 h; Heating;