1.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 °C / Inert atmosphere 1.2: 10 h / 20 °C / Inert atmosphere 2.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 1 h / 20 °C View Scheme

1: 1.) butyllithium / 1.) THF, RT, 20 min, 2.) THF, 10 min 2: 93 percent / tetrabutylammonium fluoride / tetrahydrofuran / 0.33 h 3: 94.4 percent / H2 / 10percent Pd/C / methanol; ethyl acetate / Ambient temperature View Scheme

1: 1.) butyllithium / 1.) THF, RT, 20 min, 2.) THF, 10 min 2: 93 percent / tetrabutylammonium fluoride / tetrahydrofuran / 0.33 h View Scheme