palladium diacetate; caesium carbonate; triphenylphosphine in 1-methyl-pyrrolidin-2-one T=90°C; 1 h; Inert atmosphere;

Pd-Cu/C; ethanolamine; triphenylphosphine in water T=80°C; 20 h; Sealed tubeInert atmosphere;

tetrakis(triphenylphosphine) palladium(0); caesium carbonate in N,N-dimethyl-formamide T=90°C; 4 h; Inert atmosphereSchlenk technique; chemoselective reaction;

1,10-phenanthroline; Cu(acetate)2*(x)H2O; sodium acetate; palladium diacetate in 1,2-dichloro-ethane T=110°C; 24 h; Molecular sieve;

copper(l) iodide; palladium; triphenylphosphine; aluminum oxide; potassium fluoride Sonogashira coupling-cyclization; 0.0583333 h; microwave irradiation (100 percent power);

copper(l) iodide; palladium; triphenylphosphine; aluminum oxide; potassium fluoride Sonogashira coupling-cyclization; 0.0583333 h; microwave irradiation (100 percent power);

1: 74 percent / NaBH4 / methanol / 6 h / Ambient temperature 2: 84 percent / pyridine / CH2Cl2 / 20 h / Ambient temperature 3: 1) sulphuryl chloride; 2) triethylamine / 1) CH2Cl2, -40 deg C, 20 min; 2) CH2Cl2, DMF, -40 to 20 deg C 4: conc. HCl / 2-methoxy-ethanol / 4 h / Heating View Scheme

1: 84 percent / pyridine / CH2Cl2 / 20 h / Ambient temperature 2: 1) sulphuryl chloride; 2) triethylamine / 1) CH2Cl2, -40 deg C, 20 min; 2) CH2Cl2, DMF, -40 to 20 deg C 3: conc. HCl / 2-methoxy-ethanol / 4 h / Heating View Scheme

1: 1) sulphuryl chloride; 2) triethylamine / 1) CH2Cl2, -40 deg C, 20 min; 2) CH2Cl2, DMF, -40 to 20 deg C 2: conc. HCl / 2-methoxy-ethanol / 4 h / Heating View Scheme

1: 1) NaOH / 1) MeOH, 0 deg C, 20 min 2) MeOH, RT, 6 h 2: 74 percent / NaBH4 / methanol / 6 h / Ambient temperature 3: 84 percent / pyridine / CH2Cl2 / 20 h / Ambient temperature 4: 1) sulphuryl chloride; 2) triethylamine / 1) CH2Cl2, -40 deg C, 20 min; 2) CH2Cl2, DMF, -40 to 20 deg C 5: conc. HCl / 2-methoxy-ethanol / 4 h / Heating View Scheme