water; sodium hydride; methyl iodide in tetrahydrofuran T=50°C; 1 h;

water; sodium hydride; methyl iodide in tetrahydrofuran T=50°C; 1 h;

Multi-step reaction with 4 steps 1: 2M potassium hydroxid / H2O / 0.75 h / 18 °C2: thionyl chloride / benzene / 0.5 h / 60 °C3: 101 mg / liquid ammonia / tetrahydrofuran / -78 - 17 °C4: 81 percent / Lawesson's reagent / toluene / 1.5 h / Heating  

Multi-step reaction with 2 steps 1: 101 mg / liquid ammonia / tetrahydrofuran / -78 - 17 °C2: 81 percent / Lawesson's reagent / toluene / 1.5 h / Heating