3-溴-4-甲基-5-三氟甲基吡啶合成路线 （共 1 条）
反应条件
1: 3-bromo-5-(trifluoromethyl)pyridine With n-butyllithium; diisopropylamine in tetrahydrofuran
T=-100 - -10°C;
2: methyl iodide in tetrahydrofuran
T=-78°C; 0.5 h;
参考文献
NOVARTIS AG; BOCK, Mark G.; GAUL, Christoph; GUMMADI, Venkateshwar Rao; SENGUPTA, Saumitra
Patent: WO2010/149755 A1, 2010 ;
Location in patent: Page/Page column 154-155; 200 ;
WO 2010/149755 A1
