反应条件
1: 2-bromo-6-chloro-3-methylpyridine With n-butyllithium in tetrahydrofuran; hexanes T=-78 - 20°C; Inert atmosphere; 2: N,N-dimethyl-formamide in tetrahydrofuran; hexanes T=-78 - 20°C; Inert atmosphere;
参考文献
AB SCIENCE; MOUSSY, Alain; BENJAHAD, Abdellah; MARTIN, Jason; CHEVENIER, Emmanuel; PEZ, Didier; SANDRINELLI, Franck; PICOUL, Willy
Patent: WO2011/86085 A1, 2011 ;
Location in patent: Page/Page column 43-44 ;
WO 2011/086085 A1