5-溴-3-(1-甲基-4-哌啶基)吲哚合成路线 （共 4 条）
反应条件
1: With hydrogen; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene; Rh(acac)2(CO)2 in tetrahydrofuran T=100°C; P=45003.6 Torr; 72 h; 2: With sulfuric acid 2 h; Heating;
参考文献
Schmidt, Axel M.; Eilbracht, Peter
Journal of Organic Chemistry, 2005 , vol. 70, # 14 p. 5528 - 5535
反应条件
sodium tetrahydroborate; acetic acid in tetrahydrofuran T=45°C;
参考文献
Shashikumar, Nellisara D.; Krishnamurthy, Ganga Naika; Rao K, Sundara Raj; Shridhara, Kanakamajalu; Naik, Halehatti S. Bhojya; Nagarajan, Kuppuswamy
Organic Process Research and Development, 2010 , vol. 14, # 4 p. 918 - 920
反应条件
triethylsilane; methanesulfonic acid in toluene T=70°C;
参考文献
Shashikumar, Nellisara D.; Krishnamurthy, Ganga Naika; Rao K, Sundara Raj; Shridhara, Kanakamajalu; Naik, Halehatti S. Bhojya; Nagarajan, Kuppuswamy
Organic Process Research and Development, 2010 , vol. 14, # 4 p. 918 - 920
反应条件
1.1: 84 percent / NaH / dimethylsulfoxide / 0.5 h / 20 °C 2.1: XANTHPHOS; H2 / Rh(acac)2(CO)2 / tetrahydrofuran / 72 h / 100 °C / 45003.6 Torr 2.2: 100 percent / aq. H2SO4 / 2 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 70, # 14 p. 5528 - 5535
