(R)-2-氨基-7-甲氧基四氢萘合成路线 （共 6 条）
参考文献
European Journal of Medicinal Chemistry, , vol. 29, # 4 p. 259 - 268
反应条件
sodium hydroxide in water; ethyl acetate
参考文献
US2010/197924 A1, ;
Page/Page column 12 ;
反应条件
1.1: dichloromethane / 0.25 h / Inert atmosphere 1.2: 15 h / 20 °C / Inert atmosphere 2.1: Pearlman's catalist; hydrogen; acetic acid / ethanol / 24.08 h / 20 °C 3.1: sodium hydroxide / water; ethyl acetate 4.1: methanol; water; isopropyl alcohol; toluene / 0.5 h / Reflux 5.1: sodium hydroxide / water; ethyl acetate View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 54, # 6 p. 1836 - 1846
反应条件
1: Pearlman's catalist; hydrogen; acetic acid / ethanol / 24.08 h / 20 °C 2: sodium hydroxide / water; ethyl acetate 3: methanol; water; isopropyl alcohol; toluene / 0.5 h / Reflux 4: sodium hydroxide / water; ethyl acetate View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 54, # 6 p. 1836 - 1846
反应条件
1: sodium hydroxide / water; ethyl acetate 2: methanol; water; isopropyl alcohol; toluene / 0.5 h / Reflux 3: sodium hydroxide / water; ethyl acetate View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 54, # 6 p. 1836 - 1846
反应条件
ammonium hydroxide; hydrogen bromide 3 h; Heating;
参考文献
Cecchi, R.; Croci, T.; Boigegrain, R.; Boveri, S.; Baroni, M.; et al.
European Journal of Medicinal Chemistry, 1994 , vol. 29, # 4 p. 259 - 268
