1: 76.3 percent / LiOH*H2O, H2O / tetrahydrofuran; methanol / 5 h / 60 °C / various bases, other time and temperature 2: 25 percent / butanol / 6 h / 105 - 110 °C View Scheme

1: 76.3 percent / LiOH*H2O, H2O / tetrahydrofuran; methanol / 5 h / 60 °C / various bases, other time and temperature 2: 71 percent / HCl(g) / diethyl ether / 0 °C View Scheme

Multi-step reaction with 2 steps 1: 76.3 percent / LiOH*H2O, H2O / tetrahydrofuran; methanol / 5 h / 60 °C / various bases, other time and temperature2: 28.6 percent / butanol / 6 h / 105 - 110 °C