1: sodium periodate / tetrahydrofuran; water / 20 °C / Inert atmosphere 2: iron; acetic acid View Scheme

1.1: sodium periodate / water; tetrahydrofuran / 6 h / 20 °C 2.1: titanium tetrachloride / dichloromethane; diethyl ether / 1 h / -78 - -50 °C 2.2: 1 h / -50 °C 3.1: Dess-Martin periodane / dichloromethane / 16 h 4.1: acetic acid; iron / 4 h View Scheme

1.1: sodium periodate / water; tetrahydrofuran / 6 h / 20 °C 2.1: titanium tetrachloride / dichloromethane; diethyl ether / 1 h / -78 - -50 °C 2.2: 1 h / -50 °C 3.1: Dess-Martin periodane / dichloromethane / 16 h View Scheme

Multi-step reaction with 2 steps 1.1: sodium periodate / water; tetrahydrofuran / 6 h / 20 °C2.1: titanium tetrachloride / dichloromethane; diethyl ether / 1 h / -78 - -50 °C2.2: 1 h / -50 °C