3-甲基-1-((2-(三甲基甲硅烷基)乙氧基)甲基)-1H-吲唑-6-胺合成路线 （共 3 条）
反应条件
hydrogen; palladium 10 on activated carbon in methanol T=25°C; 12 h;
参考文献
ABBOTT LABORATORIES; CALDERWOOD, David, J.; WILSON, Noel, S.; COX, Philip; HOEMANN, Michael, Z.; CLAPHAM, Bruce; MULLEN, Kelly, D.; VASUDEVAN, Anil; VILLAMIL, Clara I; LI, Bin; SOMAL, Gagandeep
Patent: WO2012/48222 A1, 2012 ;
Location in patent: Page/Page column 212 ;
WO 2012/048222 A1
反应条件
1.1: sodium hydride / tetrahydrofuran; mineral oil / 0.5 h / 0 °C 1.2: 12 h / 20 °C 2.1: hydrogen / palladium 10 on activated carbon / methanol / 12 h / 25 °C View Scheme
参考文献
ABBOTT LABORATORIES; CALDERWOOD, David, J.; WILSON, Noel, S.; COX, Philip; HOEMANN, Michael, Z.; CLAPHAM, Bruce; MULLEN, Kelly, D.; VASUDEVAN, Anil; VILLAMIL, Clara I; LI, Bin; SOMAL, Gagandeep
Patent: WO2012/48222 A1, 2012 ;
WO 2012/048222 A1
反应条件
1.1: sodium hydride / tetrahydrofuran; mineral oil / 0.5 h / 0 °C 1.2: 12 h / 20 °C 2.1: hydrogen / palladium 10 on activated carbon / methanol / 12 h / 25 °C View Scheme
参考文献
ABBOTT LABORATORIES; CALDERWOOD, David, J.; WILSON, Noel, S.; COX, Philip; HOEMANN, Michael, Z.; CLAPHAM, Bruce; MULLEN, Kelly, D.; VASUDEVAN, Anil; VILLAMIL, Clara I; LI, Bin; SOMAL, Gagandeep
Patent: WO2012/48222 A1, 2012 ;
WO 2012/048222 A1
