N-叔丁氧羰基-N-甲乙二胺合成路线 （共 10 条）
反应条件
hydrogen; nickel in methanol P=3040 Torr; 72 h; Ambient temperature;
参考文献
Journal of Medicinal Chemistry, , vol. 39, # 16 p. 3070 - 3088
反应条件
triethylamine in acetonitrile T=-30 - 20°C; 2 h;
参考文献
US2008/318957 A1, ;
Page/Page column 72; 73 ;
反应条件
sodium hydroxide in methanol T=15 - 35°C; 48 h;
参考文献
Journal of Medicinal Chemistry, , vol. 44, # 25 p. 4492 - 4496
反应条件
hydrazine hydrate in methanol T=60°C; 4.5 h; Reflux;
参考文献
Organic Preparations and Procedures International, , vol. 41, # 4 p. 301 - 307
反应条件
1: 95 percent / NaOH / dioxane 2: 69 percent / chloroformic acid ethyl ester, Et3N, 20percent aq. NH3 / tetrahydrofuran 3: 80 percent / NMM, trifluoroacetic anhydride / tetrahydrofuran / 3 h / Ambient temperature 4: 86 percent / H2, NH3-sat. EtOH / Raney-Ni / 12 h / 50 °C / 22501.8 Torr View Scheme
参考文献
Synthesis, , # 10 p. 1246 - 1258
反应条件
triethylamine in tetrahydrofuran; N-methyl-acetamide; ethyl acetate
参考文献
US6369034 B1, ;
US 6369034 B1
反应条件
diborane in tetrahydrofuran Yield given;
参考文献
Tetrahedron Letters, , vol. 38, # 30 p. 5335 - 5338
反应条件
1: Et3N 2: 25percent NH3(H2O) 3: 98 percent / TFAA / pyridine 4: 67 percent / H2, NH3 / Raney-Ni View Scheme
参考文献
Tetrahedron Letters, , vol. 38, # 30 p. 5335 - 5338
反应条件
in tetrahydrofuran Ambient temperature;
参考文献
Journal of Medicinal Chemistry, , vol. 33, # 1 p. 97 - 101
反应条件
1: 80 percent / diethyl azodicarboxylate, triphenylphosphine / tetrahydrofuran / 14 h 2: 70 percent / 55percent aq. hydrazine hydrate / ethanol / 24 h / Ambient temperature View Scheme
参考文献
Synthetic Communications, , vol. 23, # 17 p. 2443 - 2449
