三甲基((3-甲基氧杂环丁烷-3-基)乙炔)硅烷合成路线 (共 1 条)
反应条件
1: 3-(2,2-dibromovinyl)-3-methyloxetane With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 0.75 h; 2: chloro-trimethyl-silane in tetrahydrofuran; hexane T=-78 - 20°C;
参考文献
AMGEN INC.; ALLEN, Jennifer; HORNE, Daniel B.; HU, Essa; KALLER, Matthew R.; MONENSCHEIN, Holger; NGUYEN, Thomas T.; REICHELT, Andreas; RZASA, Robert M.
Patent: WO2011/143495 A1, 2011 ;
Location in patent: Page/Page column 237 ;
WO 2011/143495 A1