6,6-二甲基-4-氧代-4,5,6,7-四氢苯并呋喃-3-羧酸合成路线 （共 2 条）
反应条件
1: With potassium hydroxide in methanol T=0 - 20°C; 16 h; 2: With methanol; sodium hydroxide; water T=20°C; 4 h; 3: With hydrogenchloride; water in methanol
参考文献
NOVARTIS AG
Patent: WO2008/101905 A1, 2008 ;
Location in patent: Page/Page column 20-21 ;
WO 2008/101905 A1
反应条件
hydrogenchloride; potassium hydroxide 1) RT, overnight, 2) 15 h; Yield given. Multistep reaction;
参考文献
Nagarajan, Kuppuswamy; Talwalker, Purnachard K.; Goud, A. Nagana; Shah, Rashmi K.; Shenoy, Sharada J.; Desai, Narasimha D.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1988 , vol. 27, # 1-12 p. 1113 - 1123
