(9H-氧杂蒽-9-基)-乙酸合成路线 （共 6 条）
反应条件
pyridine T=65 - 95°C; 6.5 h;
参考文献
Bristol-Myers Squibb Company
Patent: US2009/75995 A1, 2009 ;
Location in patent: Page/Page column 53-54 ;
反应条件
in 1-methyl-pyrrolidin-2-one T=100°C; 1 h;
参考文献
Troxler, Thomas; Hurth, Konstanze; Mattes, Henri; Prashad, Mahavir; Schoeffter, Philippe; Langenegger, Daniel; Enz, Albert; Hoyer, Daniel
Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 5 p. 1305 - 1309
参考文献
Yakugaku Zasshi, , vol. 77, p. 1145,1148
Chem.Abstr., , p. 5403
参考文献
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, , vol. 143, p. 59
Annales de Chimie (Cachan, France), , vol. <9> 13, p. 91
反应条件
1: SOCl2 / benzene / Heating
2: diethyl ether / 20 °C
3: PhCOOAg; aq. Et3N / tetrahydrofuran / 20 °C
4: LiAlH4 / tetrahydrofuran / Heating
View Scheme
参考文献
Pellicciari, Roberto; Costantino, Gabriele; Marinozzi, Maura; Macchiarulo, Antonio; Amori, Laura; Josef Flor, Peter; Gasparini, Fabrizio; Kuhn, Rainer; Urwyler, Stephan
Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 24 p. 3179 - 3182
反应条件
1: SOCl2 / benzene / Heating
2: diethyl ether / 20 °C
3: PhCOOAg; aq. Et3N / tetrahydrofuran / 20 °C
4: LiAlH4 / tetrahydrofuran / Heating
5: PCC / CH2Cl2 / 20 °C
View Scheme
参考文献
Pellicciari, Roberto; Costantino, Gabriele; Marinozzi, Maura; Macchiarulo, Antonio; Amori, Laura; Josef Flor, Peter; Gasparini, Fabrizio; Kuhn, Rainer; Urwyler, Stephan
Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 24 p. 3179 - 3182
