3,6-双[[(1,1-二甲基乙基)二甲基甲硅烷基]氧基]-9H-占顿醇-9-酮合成路线 （共 4 条）
反应条件
1H-imidazole in N,N-dimethyl-formamide
参考文献
Martinez-Peragon, Angela; Miguel, Delia; Jurado, Rocio; Justicia, Jose; Alvarez-Pez, Jose M.; Cuerva, Juan M.; Crovetto, Luis
Chemistry - A European Journal, 2014 , vol. 20, # 2 p. 447 - 455
反应条件
1: 100 percent / H2O / 220 °C / 1900 Torr 2: 64 percent / imidazole / dimethylformamide / 20 °C View Scheme
参考文献
Shieh, Peyton; Hangauer, Matthew J.; Bertozzi, Carolyn R.
Journal of the American Chemical Society, 2012 , vol. 134, # 42 p. 17428 - 17431
反应条件
1.1: t-BuLi / tetrahydrofuran / 1 h / -100 °C
1.2: 85 percent / aq. HCl / tetrahydrofuran / 0.17 h
2.1: 94 percent / TFA / CH2Cl2 / 1 h / 20 °C
View Scheme
参考文献
Mineno, Tomoko; Ueno, Tasuku; Urano, Yasuteru; Kojima, Hirotatsu; Nagano, Tetsuo
Organic Letters, 2006 , vol. 8, # 26 p. 5963 - 5966
反应条件
1: With tert.-butyl lithium in tetrahydrofuran
T=-100°C; 1 h;
2: With hydrogenchloride in tetrahydrofuran
0.166667 h;
参考文献
Mineno, Tomoko; Ueno, Tasuku; Urano, Yasuteru; Kojima, Hirotatsu; Nagano, Tetsuo
Organic Letters, 2006 , vol. 8, # 26 p. 5963 - 5966
