3-(2-呋喃基)-L-丙氨酸合成路线 （共 15 条）
反应条件
ammonium hydroxide; anhydrous cobalt diacetate in water T=38°C; acylase I;
参考文献
Bladon, Christine M.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1990 , # 4 p. 1151 - 1158
反应条件
potassium hydroxide; Aspergillus acylase I pH 7.5-8.0;
参考文献
Chenault, H. Keith; Dahmer, Juergen; Whitesides, George M.
Journal of the American Chemical Society, 1989 , vol. 111, # 16 p. 6354 - 6364
反应条件
ammonium hydroxide; carbon dioxide; phenylalanine ammonia-lyase T=30°C; pH=10.2; 72 h;
参考文献
Paizs, Csaba; Katona, Adrian; Retey, Janos
Chemistry - A European Journal, 2006 , vol. 12, # 10 p. 2739 - 2744
反应条件
potassium hydroxide; potassium phosphate buffer; porcine kidney acylase I T=40°C; relative initial rate of hydrolysis, also with Aspergillus acylase I as a catalyst; with or without CoCl2;
参考文献
Journal of the American Chemical Society, , vol. 111, # 16 p. 6354 - 6364
反应条件
1: 91 percent / toluene / 2 h / Heating 2: 90 percent / aq. KOH / 4 h / Heating 3: 66 percent / phenylalanine ammonia-lyase; aq. NH3; CO2 / 72 h / 30 °C / pH 10.2 View Scheme
参考文献
Chemistry - A European Journal, , vol. 12, # 10 p. 2739 - 2744
反应条件
1: 82 percent / KOH / ethanol; H2O / 3 h / Ambient temperature 2: 80 percent / dioxane / 39 h / Heating 3: 54 percent / KOH / ethanol; H2O / 17 h / Heating 4: 63 percent / cobalt acetate, 25percent aq. NH4OH / H2O / 38 °C / acylase I View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 4 p. 1151 - 1158
反应条件
1: 54 percent / KOH / ethanol; H2O / 17 h / Heating 2: 63 percent / cobalt acetate, 25percent aq. NH4OH / H2O / 38 °C / acylase I View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 4 p. 1151 - 1158
反应条件
1: 80 percent / dioxane / 39 h / Heating 2: 54 percent / KOH / ethanol; H2O / 17 h / Heating 3: 63 percent / cobalt acetate, 25percent aq. NH4OH / H2O / 38 °C / acylase I View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 4 p. 1151 - 1158
反应条件
1: sodium methylate / 2 h / Reflux 2: Ba(OH)2 / 24 h / 20 °C 3: 1,4-dioxane / 24 h / Reflux 4: potassium hydroxide / 17 h / 20 °C 5: porcine kidney acylase 1; cobalt(II) chloride / Enzymatic reaction View Scheme
参考文献
ChemBioChem, , vol. 11, # 12 p. 1720 - 1726
反应条件
1: Ba(OH)2 / 24 h / 20 °C 2: 1,4-dioxane / 24 h / Reflux 3: potassium hydroxide / 17 h / 20 °C 4: porcine kidney acylase 1; cobalt(II) chloride / Enzymatic reaction View Scheme
参考文献
ChemBioChem, , vol. 11, # 12 p. 1720 - 1726
