1-(5-溴-2-羟基苯基)-3-苯基丙-2-烯-1-酮合成路线 （共 6 条）
反应条件
sodium hydroxide in ethanol
参考文献
Du, Zhiyun; Ng, Huifen; Zhang, Kun; Zeng, Huaqiang; Wang, Jian
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 20 p. 6930 - 6933
反应条件
1: acetic anhydride / Heating 2: AlCl3 / 120 °C 3: NaOH / ethanol View Scheme
参考文献
Dandegaonker,S.H.; Revankar,G.R.
Monatshefte fuer Chemie, 1965 , vol. 96, p. 450 - 460
反应条件
1: AlCl3 / 120 °C 2: NaOH / ethanol View Scheme
参考文献
Dandegaonker,S.H.; Revankar,G.R.
Monatshefte fuer Chemie, 1965 , vol. 96, p. 450 - 460
参考文献
Feuerstein; v.Kostanecki
Chemische Berichte, 1898 , vol. 31, p. 718,719
反应条件
copper(l) iodide; oxygen T=50°C; oxa-Michael-oxidation; P=760.051 Torr; 48 h; Ionic liquid;
参考文献
Organic and Biomolecular Chemistry, , vol. 9, # 20 p. 6930 - 6933
反应条件
1: 3-phenyl-1-(2'-hydroxy-5'-bromophenyl)-2-propen-1-one With zinc(II) chloride in dichloromethane
T=20°C; 12 h;
2: 3,4,5-trimethoxyphenylboronic acid With tetrakis(triphenylphosphine) palladium(0); sodium carbonate in ethylene glycol dimethyl ether
Suzuki coupling; Inert atmosphereReflux;
3: With dihydrogen peroxide in tetrahydrofuran; water
T=0°C; 1 h; regioselective reaction;
参考文献
Tang; Li, Wen; Gao, Zhangyong; Zhang, Lianpeng; Ma, Qiushi
Chinese Journal of Chemistry, 2012 , vol. 30, # 3 p. 585 - 589
