N-(2,3-二氯苯基)-2,2,2-三氟乙酰胺合成路线 (共 2 条)
参考文献
Cambie, Richard C.; Clark, George R.; Coombe, Sheryl L.; Coulson, Sally A.; Rutledge, Peter S.; Woodgate, Paul D.
Journal of Organometallic Chemistry, 1996 , vol. 507, # 1-2 p. 1 - 21
反应条件
1: 88 percent / potassium carbonate / dimethylformamide / 0.5 h / 20 °C
2: 81 percent / aq. potassium carbonate / methanol / 1 h / 20 °C
View Scheme
参考文献
Minutolo, Filippo; Antonello, Michela; Bertini, Simone; Ortore, Gabriella; Placanica, Giorgio; Rapposelli, Simona; Sheng, Shubin; Carlson, Kathryn E.; Katzenellenbogen, Benita S.; Katzenellenbogen, John A.; Macchia, Marco
Journal of Medicinal Chemistry, 2003 , vol. 46, # 19 p. 4032 - 4042