4-氨基-3-苯并(b)呋喃-2-基丁酸合成路线 （共 4 条）
反应条件
sodium hydroxide in ethanol 1 h; Heating;
参考文献
Berthelot; Vaccher; Musadad; Flouquet; Debaert; Luyckx
Journal of Medicinal Chemistry, 1987 , vol. 30, # 4 p. 743 - 746
反应条件
1: Zn / benzene / Heating 2: P2O5 / toluene / 3 h / Heating 3: 70 percent / NBS / CCl4 / 48 h / Heating 4: 60 percent / NH3 (liquid) / tetrahydrofuran / 3 h 5: H2 / Ra-Ni / ethanol / 760 Torr / Ambient temperature 6: 90 percent / 10N NaOH / aq. ethanol / 1 h / Heating View Scheme
参考文献
Berthelot; Vaccher; Musadad; Flouquet; Debaert; Luyckx
Journal of Medicinal Chemistry, 1987 , vol. 30, # 4 p. 743 - 746
反应条件
1: 70 percent / NBS / CCl4 / 48 h / Heating 2: 60 percent / NH3 (liquid) / tetrahydrofuran / 3 h 3: H2 / Ra-Ni / ethanol / 760 Torr / Ambient temperature 4: 90 percent / 10N NaOH / aq. ethanol / 1 h / Heating View Scheme
参考文献
Berthelot; Vaccher; Musadad; Flouquet; Debaert; Luyckx
Journal of Medicinal Chemistry, 1987 , vol. 30, # 4 p. 743 - 746
反应条件
1: H2 / Ra-Ni / ethanol / 760 Torr / Ambient temperature 2: 90 percent / 10N NaOH / aq. ethanol / 1 h / Heating View Scheme
参考文献
Berthelot; Vaccher; Musadad; Flouquet; Debaert; Luyckx
Journal of Medicinal Chemistry, 1987 , vol. 30, # 4 p. 743 - 746
