1,3-双(4-氯苯基)尿素合成路线 （共 117 条）
反应条件
in pyridine; water
T=20°C; Condensation; 2 h;
参考文献
Blanco, Jose L. Jimenez; Barria, Claudio Saitz; Benito, Juan M.; Mellet, Carmen Ortiz; Fuentes, Jose; Santoyo-Gonzales, Francisco; Fernandez, Jose M. Garcia
Synthesis, 1999 , # 11 p. 1907 - 1914
反应条件
caesium carbonate; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene; tris(dibenzylideneacetone)dipalladium(0) chloroform complex in 1,4-dioxane
T=100°C; 10 h;
参考文献
Artamkina, Galina A.; Sergeev, Alexey G.; Beletskaya, Irina P.
Tetrahedron Letters, 2001 , vol. 42, # 26 p. 4381 - 4384
反应条件
4-(N,N-dimethlyamino)pyridine; W(CO)6; iodine in dichloromethane
T=40°C; P=60804.1 Torr; 20 h;
参考文献
Zhang, Li; Darko, Ampofo K.; Johns, Jennifer I.; McElwee-White, Lisa
European Journal of Organic Chemistry, 2011 , # 31 p. 6261 - 6268
反应条件
caesium carbonate; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene; tris(dibenzylideneacetone)dipalladium(0) chloroform complex in 1,4-dioxane
T=100°C; 10 h;
参考文献
Artamkina; Sergeev; Beletskaya
Russian Journal of Organic Chemistry, 2002 , vol. 38, # 4 p. 538 - 545
反应条件
tris(dibenzylideneacetone)dipalladium(0) chloroform complex; caesium carbonate; (9,9-dimethyl-9H-xanthene-4,5-diyl)bis(bis(3,5-bis(trifluoromethyl)phenyl)phosphine) in 1,4-dioxane
T=100°C; 1 h;
参考文献
Sergeev, Alexey G.; Artamkina, Galina A.; Beletskaya, Irina P.
Tetrahedron Letters, 2003 , vol. 44, # 25 p. 4719 - 4723
反应条件
1: in tetrahydrofuran
T=20°C;
2: With 4-(N,N-dimethlyamino)pyridine in tetrahydrofuran
Reflux;
参考文献
Lee, Hyung-Geun; Kim, Min-Jung; Park, Song-Eun; Kim, Jeum-Jong; Kim, Bo Ram; Lee, Sang-Gyeong; Yoon, Yong-Jin
Synlett, 2009 , # 17 p. 2809 - 2814
反应条件
potassium tert-butylate; oxygen in tert-butyl alcohol
T=40°C; 20 h;
参考文献
Kim, Yong Hae; Kim, Hyung Jin; Yon, Gyu Hwan
Journal of the Chemical Society, Chemical Communications, 1984 , # 16 p. 1064 - 1065
反应条件
zirconium oxide; molybdenum in 1,2-dichloro-benzene
T=69.85°C; Condensation; 6 h;
参考文献
Reddy, Benjaram M.; Reddy, Vangala R.
Synthetic Communications, 1999 , vol. 29, # 16 p. 2789 - 2794
反应条件
4-(N,N-dimethlyamino)pyridine
T=80 - 90°C; 6 h;
参考文献
Chemagis Ltd.
Patent: US2007/249823 A1, 2007 ;
Location in patent: Page/Page column 10; 11 ;
反应条件
sodium hydroxide in acetone
16.5 h;
参考文献
Howbert; Grossman; Crowell; Rieder; Harper; Kramer; Tao; Aikins; Poore; Rinzel; Grindey; Shaw; Todd
Journal of Medicinal Chemistry, 1990 , vol. 33, # 9 p. 2393 - 2407
