反应条件
Stage #1: <b>With</b> <a href="#" onclick="return RXDsubstances(event, this, '1209227', constants.ctx, '0')">n-butyllithium</a>; <a href="#" onclick="return RXDsubstances(event, this, '4526709', constants.ctx, '0')">LiDMAE</a> <b>in</b> <a href="#" onclick="return RXDsubstances(event, this, '1730733', constants.ctx, '0')">hexane</a> <br />T=-45°C; Inert atmosphere; <br />Stage #2: <b>With</b> <a href="#" onclick="return RXDsubstances(event, this, '1740341', constants.ctx, '0')">1,2,2-trichloro-1,1,2-trichloro-ethane</a> <b>in</b> <a href="#" onclick="return RXDsubstances(event, this, '102391', constants.ctx, '0')">tetrahydrofuran</a>; <a href="#" onclick="return RXDsubstances(event, this, '1730733', constants.ctx, '0')">hexane</a> <br />T=-78°C; 1 h; Inert atmosphere; <br />Stage #3: <b>With</b> <a href="#" onclick="return RXDsubstances(event, this, '3587155', constants.ctx, '0')">water</a> <br />T=-78°C; Inert atmosphere; regioselective reaction; <br />
参考文献
Chartoire, Anthony; Comoy, Corinne; Fort, Yves Journal of Organic Chemistry, 2010 , vol. 75, # 7 p. 2227 - 2235
