1: 92 percent / 1) NaH / dimethylformamide / 1) r.t., 1 h, 2) 80 deg C, 7 h 2: 45 percent / Na2HPO4, Na/Hg / methanol / 0.75 h / 0 °C 3: 40 percent / Na/Hg / methanol / 48 h / 25 °C 4: 65 percent / CsF / tetrahydrofuran / 3 h / Heating View Scheme

Multi-step reaction with 2 steps 1: 92 percent / 1) NaH / dimethylformamide / 1) r.t., 1 h, 2) 80 deg C, 7 h2: 45 percent / Na2HPO4, Na/Hg / methanol / 0.75 h / 0 °C