1: 2-phenyl-1,3-thiazole-4-carboxylic acid hydrazide With water; sodium hydrogencarbonate in 1,4-dioxane T=20°C; 0.0833333 h; 2: bromocyane in 1,4-dioxane T=20°C;

1.1: ethanol / 6 h / |Reflux 2.1: hydrazine hydrate / ethanol / 2 h / 20 °C 3.1: sodium hydrogencarbonate; water / 1,4-dioxane / 0.08 h / 20 °C 3.2: 20 °C View Scheme

1.1: hydrazine hydrate / ethanol / 2 h / 20 °C 2.1: sodium hydrogencarbonate; water / 1,4-dioxane / 0.08 h / 20 °C 2.2: 20 °C View Scheme