1: oxalic acid dimethyl ester With sodium methylate in methanol
Claisen condensation; 0.25 h;
2: para-methylacetophenone in methanol
T=30°C; Claisen condensation; 0.0833333 h; Microwave irradiation;
参考文献
Reddy, Tummala R. K.; Li, Chan; Guo, Xiaoxia; Myrvang, Helene K.; Fischer, Peter M.; Dekker, Lodewijk V.
Journal of Medicinal Chemistry, 2011 , vol. 54, # 7 p. 2080 - 2094
1: para-methylacetophenone With polymer-supported [(hydroxy(sulfonyloxy)iodo]benzene in acetonitrile
16 h; Heating;
2: ethanethioamide With potassium carbonate in acetonitrile
6 h; Heating;
1: 10percent KOH / methanol
2: 75 percent / P2I4 / CHCl3 / 0.33 h / Ambient temperature
View Scheme
参考文献
Horspool, William M.; Khalaf, Abedawn I.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1989 , p. 1147 - 1152