乙基7-(4-甲基苯基)-7-氧代庚酸酯合成路线 (共 1 条)
反应条件
1: 6-bromohexanoic acid ethyl ester With magnesium; lithium chloride; zinc(II) chloride in tetrahydrofuran T=20°C; 2.5 h; Inert atmosphere; 2: With CuCN*2LiCl in tetrahydrofuran T=-30°C; Inert atmosphere; 3: 4-methyl-benzoyl chloride in tetrahydrofuran T=-30°C; Inert atmosphere;
参考文献
Bluemke, Tobias D.; Piller, Fabian M.; Knochel, Paul
Chemical Communications, 2010 , vol. 46, # 23 p. 4082 - 4084