1: potassium carbonate / acetonitrile / 23 - 25 °C 2: palladium 10 on activated carbon; hydrogen / methanol / 20 °C / 2068.65 Torr / Large scale reaction 3: sodium tetrahydroborate / 1,2-dichloro-ethane / 30 - 50 °C / Large scale reaction 4: hydrogenchloride / 4 h / Reflux; Large scale reaction View Scheme

1: potassium carbonate / acetonitrile / 23 - 25 °C 2: palladium 10 on activated carbon; hydrogen / methanol / 20 °C / 2068.65 Torr / Large scale reaction 3: sodium tetrahydroborate / 1,2-dichloro-ethane / 30 - 50 °C / Large scale reaction View Scheme

Multi-step reaction with 2 steps 1: potassium carbonate / acetonitrile / 23 - 25 °C2: palladium 10 on activated carbon; hydrogen / methanol / 20 °C / 2068.65 Torr / Large scale reaction