1: With C42H58N4O2Ti in toluene T=110°C; 14 h; Inert atmosphereSchlenk technique; 2: With formic acid; [{(S,S)-Ts-dpen}(η6-p-cymene)RuCl]; triethylamine in N,N-dimethyl-formamide; toluene T=20°C; 14 h; Inert atmosphereSchlenk technique; enantioselective reaction;