1: With sodium ethanolate in ethanol
T=20 - 60°C; 10 h; Inert atmosphere;
2: With hydrogenchloride in ethanol; water
T=40 - 50°C; pH=3; Product distribution / selectivity;
参考文献
Shanghai Institute of Materia Medica, Chinese Academy of Sciences; Topharman Shangai Co., Ltd.
Patent: US2011/263860 A1, 2011 ;
Location in patent: Page/Page column 7 ;