1: ammonium formate, Pd(OAc)2 / 10percent Pd/C / ethyl acetate; methanol / 6 h / Ambient temperature 2: dicyclohexylcarbodiimide (DCC) / ethyl acetate / 1.) -20 deg C, overnight, 2.) RT, 4 h 3: ammonium formate, Pd(OAc)2 / 10percent Pd/C / ethanol; dimethylformamide / 7 h / Ambient temperature 4: dicyclohexylcarbodiimide (DCC) / ethyl acetate; dimethylformamide / 1.) -5 deg C, overnight, 2.) RT, 4 h 5: ammonium formate, Pd(OAc)2 / 10percent Pd/C / methanol; dimethylformamide / 7 h / Ambient temperature 6: dicyclohexylcarbodiimide (DCC) / ethyl acetate; dimethylformamide / 1.) -5 deg C, overnight, 2.) RT, 4 h 7: 71 percent / anisole, TFA / CH2Cl2 View Scheme

With  triethylamine; dicyclohexyl-carbodiimide in  dichloromethane; N,N-dimethyl-formamide  1.) -20 deg C, overnight, 2.) RT, 4 h;   

Multi-step reaction with 2 steps 1: ammonium formate, Pd(OAc)2 / 10percent Pd/C / ethyl acetate; methanol / 6 h / Ambient temperature2: dicyclohexylcarbodiimide (DCC) / ethyl acetate / 1.) -20 deg C, overnight, 2.) RT, 4 h  

Multi-step reaction with 4 steps 1: ammonium formate, Pd(OAc)2 / 10percent Pd/C / ethyl acetate; methanol / 6 h / Ambient temperature2: dicyclohexylcarbodiimide (DCC) / ethyl acetate / 1.) -20 deg C, overnight, 2.) RT, 4 h3: ammonium formate, Pd(OAc)2 / 10percent Pd/C / ethanol; dimethylformamide / 7 h / Ambient temperature4: dicyclohexylcarbodiimide (DCC) / ethyl acetate; dimethylformamide / 1.) -5 deg C, overnight, 2.) RT, 4 h  

Multi-step reaction with 6 steps 1: ammonium formate, Pd(OAc)2 / 10percent Pd/C / ethyl acetate; methanol / 6 h / Ambient temperature2: dicyclohexylcarbodiimide (DCC) / ethyl acetate / 1.) -20 deg C, overnight, 2.) RT, 4 h3: ammonium formate, Pd(OAc)2 / 10percent Pd/C / ethanol; dimethylformamide / 7 h / Ambient temperature4: dicyclohexylcarbodiimide (DCC) / ethyl acetate; dimethylformamide / 1.) -5 deg C, overnight, 2.) RT, 4 h5: ammonium formate, Pd(OAc)2 / 10percent Pd/C / methanol; dimethylformamide / 7 h / Ambient temperature6: dicyclohexylcarbodiimide (DCC) / ethyl acetate; dimethylformamide / 1.) -5 deg C, overnight, 2.) RT, 4 h