水蛭蛋白酶抑制剂C(60-63)合成路线 （共 5 条）
反应条件
hydrogen; palladium in N,N-dimethyl-formamide
参考文献
Tsuboi; Takeda; Okada; Nagamatsu; Yamamoto
Chemical and Pharmaceutical Bulletin, 1991 , vol. 39, # 1 p. 184 - 186
反应条件
1: 97 percent 2: 7.2 N HCl-dioxane 3: 48.9 percent 4: 7.2 N HCl-dioxane 5: 75.4 percent / diphenylphosphorylazide, triethylamine / dimethylformamide / 4 °C 6: 85.7 percent / hydrogen / palladium / dimethylformamide View Scheme
参考文献
Tsuboi; Takeda; Okada; Nagamatsu; Yamamoto
Chemical and Pharmaceutical Bulletin, 1991 , vol. 39, # 1 p. 184 - 186
反应条件
1: 48.9 percent 2: 7.2 N HCl-dioxane 3: 75.4 percent / diphenylphosphorylazide, triethylamine / dimethylformamide / 4 °C 4: 85.7 percent / hydrogen / palladium / dimethylformamide View Scheme
参考文献
Tsuboi; Takeda; Okada; Nagamatsu; Yamamoto
Chemical and Pharmaceutical Bulletin, 1991 , vol. 39, # 1 p. 184 - 186
反应条件
1: 97 percent 2: 7.2 N HCl-dioxane 3: 48.9 percent 4: 7.2 N HCl-dioxane 5: 75.4 percent / diphenylphosphorylazide, triethylamine / dimethylformamide / 4 °C 6: 85.7 percent / hydrogen / palladium / dimethylformamide View Scheme
参考文献
Tsuboi; Takeda; Okada; Nagamatsu; Yamamoto
Chemical and Pharmaceutical Bulletin, 1991 , vol. 39, # 1 p. 184 - 186
反应条件
1: 7.2 N HCl-dioxane 2: 48.9 percent 3: 7.2 N HCl-dioxane 4: 75.4 percent / diphenylphosphorylazide, triethylamine / dimethylformamide / 4 °C 5: 85.7 percent / hydrogen / palladium / dimethylformamide View Scheme
参考文献
Tsuboi; Takeda; Okada; Nagamatsu; Yamamoto
Chemical and Pharmaceutical Bulletin, 1991 , vol. 39, # 1 p. 184 - 186
