4-[2-(甲基-2-吡啶基氨基)乙氧基]苯甲醛合成路线 (共 15 条)
反应条件
piperazinomethyl polystyrene in toluene T=88°C; 24 h;
参考文献
Li, Xin; Abell, Chris; Warrington, Brian H; Ladlow, Mark
Organic and biomolecular chemistry, 2003 , vol. 1, # 24 p. 4392 - 4395
反应条件
1: With pyrrolidine; acetic acid in toluene T=110°C; 2 h; 2: With diethyl-1,4-dihydro-2,6-dimethyl-3,5-pyridine dicarboxylate; silica gel in toluene 13 h; Heating / reflux; Product distribution / selectivity;
参考文献
WO2005/108394 A1, ;
Page/Page column 10 - 11 ;
反应条件
1: piperidine / toluene / 2 h / 80 °C 2: iodine; magnesium / methanol / 3 h / Reflux View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 2 p. 924 - 928
反应条件
pyrrolidine; acetic acid in toluene 3 h; HeatingReflux;
参考文献
Lopez, Ernesto Duran
Patent: US2009/234128 A1, 2009 ;
Location in patent: Page/Page column 4 ;